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Search Results for " menin-mll inhibitor "

20

Compounds

Cat No. Product Name Synonyms Targets
T9399 Menin-MLL inhibitor 20 Epigenetic Reader Domain , Histone Methyltransferase
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.
T2649 Menin-MLL inhibitor MI-2 Menin-MLL Inhibitor,MI2,MI-2,Menin-MLL inhibitor 2,MI 2 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
T2643 MI-3 Menin-MLL Inhibitor,Menin-MLL inhibitor 3,MI 3 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).
T12002 Menin-MLL inhibitor 4 Others
Menin-MLL inhibitor 4 has antitumor activity.Menin-MLL inhibitor 4 is an inhibitor of Menin- MLL (mixed-lineage leukemia protein) interaction .
T79737 Menin-MLL inhibitor 29 Epigenetic Reader Domain
Menin-MLL Inhibitor 29 (Compound C1) is a Menin-MLL protein-protein interaction (PPI) inhibitor that demonstrates high affinity to Menin with a dissociation constant (K D) of 138 nM and impedes Menin's interaction with M...
T12943 SNDX-5613 Epigenetic Reader Domain , Histone Methyltransferase
SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias.
T13336 VTP50469 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
T72360 Menin-MLL inhibitor 26
Menin-MLL inhibitor 26 is a Menin-MLL inhibitor. Menin-MLL inhibitor 26 also is an active reference. Menin-MLL inhibitor 26 can inhibits cell growth. Menin-MLL inhibitor 26 can be used for the research of leukemia .
T79117 Menin-MLL inhibitor 27 Epigenetic Reader Domain
Menin-MLL inhibitor 27 effectively inhibits the interaction between Menin and MLL, serving as a potential tool in cancer research, particularly for acute myeloid leukemia (AML) [1].
T78151 Bleximenib oxalate Menin-MLL inhibitor 24 oxalate Epigenetic Reader Domain
Menin-MLL Inhibitor 24 (compound A) oxalate, a menin-mixed-lineage leukemia 1 (menin-MLL) inhibitor, is utilized in cancer research [1].
T72135 (1s,4s)-Menin-MLL inhibitor-23
(1s,4s)-Menin-MLL Inhibitor-23, an enantiomer of Menin-MLL Inhibitor-23 (Example 99A), functions as an inhibitor of the menin-MLL interaction [1].
T28036 MI-2-2 MI22,MI 2 2 Histone Methyltransferase
MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.
T69628 Iptacopan hydrochloride hydrate
Iptacopan hydrochloride hydrate is a highly potent and highly selective factor B inhibitor.
TQ0069 MI-503 Epigenetic Reader Domain , Histone Methyltransferase
MI-503 is a highly effective and orally bioavailable inhibitor of the menin-mLL interaction.
T11925 M‑89 Epigenetic Reader Domain , Histone Methyltransferase
M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia...
T16072 MI-538 Epigenetic Reader Domain , Histone Methyltransferase
MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).
TQ0058 MI-463 Epigenetic Reader Domain , Histone Methyltransferase
MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).
T22978 MI-2 (hydrochloride) Others
MI-2 (Menin-MLL Inhibitor) is an effective menin-MLL interaction inhibitor (IC50: 446 ± 28 nM).
T24484 ML399 VU-0516340,VU 0516340,ML-399,VU0516340,ML 399
ML399 is the menin-- MLL interaction inhibitor that acts by demonstrating strong and selective effects in MLL leukemia cells and validating specific mechanism of action.
T15831 M-525 Others
M-525 binds to menin (IC50: 3 nM) and achieves low nanomolar potencies in cell growth inhibition and in the suppression of MLL regulated gene expression in MLL leukemia cells. M-525 is a first-in-class, highly potent, ir...

Compounds

Menin-MLL inhibitor 20
T9399
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
Menin-MLL inhibitor MI-2
T2649
Synonym: Menin-MLL Inhibitor,MI2,MI-2,Menin-MLL inhibitor 2,MI 2
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
MI-3
T2643
Synonym: Menin-MLL Inhibitor,Menin-MLL inhibitor 3,MI 3
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
Menin-MLL inhibitor 4
T12002
Synonym:
Target: Others
Menin-MLL inhibitor 29
T79737
Synonym:
Target: Epigenetic Reader Domain
SNDX-5613
T12943
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
VTP50469
T13336
Synonym:
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
Menin-MLL inhibitor 26
T72360
Synonym:
Target:
Menin-MLL inhibitor 27
T79117
Synonym:
Target: Epigenetic Reader Domain
Bleximenib oxalate
T78151
Synonym: Menin-MLL inhibitor 24 oxalate
Target: Epigenetic Reader Domain
(1s,4s)-Menin-MLL inhibitor-23
T72135
Synonym:
Target:
MI-2-2
T28036
Synonym: MI22,MI 2 2
Target: Histone Methyltransferase
Iptacopan hydrochloride hydrate
T69628
Synonym:
Target:
MI-503
TQ0069
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
M‑89
T11925
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
MI-538
T16072
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
MI-463
TQ0058
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
MI-2 (hydrochloride)
T22978
Synonym:
Target: Others
ML399
T24484
Synonym: VU-0516340,VU 0516340,ML-399,VU0516340,ML 399
Target:
M-525
T15831
Synonym:
Target: Others
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TargetMol